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The LaBella Lab
University of North Carolina at Charlotte

Publications
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Solé-Navais P, Juodakis J, Ytterberg K, Wu X, Bradfield JP, Vaudel M, LaBella AL, Helgeland Ø, Flatley C, Geller F, Finel M. Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism. Nature communications. 2024 Aug 30;15(1):7550.


Abraham A, LaBella AL, Benton ML, Rokas A, Capra JA.
GSEL: a fast, flexible python package for detecting signatures of diverse evolutionary forces on genomic regions.
Bioinformatics. 2023 Jan 1;39(1):btad037.
GSEL: a fast, flexible python package for detecting signatures of diverse evolutionary forces on genomic regions.
Bioinformatics. 2023 Jan 1;39(1):btad037.


Solé-Navais P, Flatley C, Steinthorsdottir V, Vaudel M, Juodakis J, Chen J, Laisk T, LaBella AL, Westergaard D, Bacelis J, Brumpton B.
Genetic effects on the timing of parturition and links to fetal birth weight.
Nature Genetics. 2023 Apr;55(4):559-67.
Genetic effects on the timing of parturition and links to fetal birth weight.
Nature Genetics. 2023 Apr;55(4):559-67.


Abraham A, LaBella AL, Capra JA, Rokas A.
Mosaic patterns of selection in genomic regions associated with diverse human traits.
PLoS genetics. 2022 Nov 7;18(11):e1010494.
Mosaic patterns of selection in genomic regions associated with diverse human traits.
PLoS genetics. 2022 Nov 7;18(11):e1010494.


Markowitz RH, LaBella AL, Shi M, Rokas A, Capra JA, Ferguson JF, Mosley JD, Bordenstein SR.
Microbiome-associated human genetic variants impact phenome-wide disease risk.
Proceedings of the National Academy of Sciences. 2022 Jun 28;119(26):e2200551119.
Microbiome-associated human genetic variants impact phenome-wide disease risk.
Proceedings of the National Academy of Sciences. 2022 Jun 28;119(26):e2200551119.


Benton ML, Abraham A, LaBella AL, Abbot P, Rokas A, Capra JA.
The influence of evolutionary history on human health and disease.
Nature Reviews Genetics. 2021 May;22(5):269-83.
The influence of evolutionary history on human health and disease.
Nature Reviews Genetics. 2021 May;22(5):269-83.


LaBella AL, Abraham A, Pichkar Y, Fong SL, Zhang G, Muglia LJ, Abbot P, Rokas A, Capra JA.
Accounting for diverse evolutionary forces reveals mosaic patterns of selection on human preterm birth loci.
Nature Communications. 2020 Jul 24;11(1):3731.
Accounting for diverse evolutionary forces reveals mosaic patterns of selection on human preterm birth loci.
Nature Communications. 2020 Jul 24;11(1):3731.


Rokas A, Mesiano S, Tamam O, LaBella A, Zhang G, Muglia L.
Developing a theoretical evolutionary framework to solve the mystery of parturition initiation.
Elife. 2020 Dec 31;9:e58343.
Developing a theoretical evolutionary framework to solve the mystery of parturition initiation.
Elife. 2020 Dec 31;9:e58343.


Ely ZA, Moon JM, Sliwoski GR, Sangha AK, Shen XX, Labella AL, Meiler J, Capra JA, Rokas A.
The impact of natural selection on the evolution and function of placentally expressed galectins.
Genome Biology and Evolution. 2019 Sep;11(9):2574-92.
The impact of natural selection on the evolution and function of placentally expressed galectins.
Genome Biology and Evolution. 2019 Sep;11(9):2574-92.


Jang YJ, LaBella AL, Feeney TP, Braverman N, Tuchman M, Morizono H, Ah Mew N, Caldovic L.
Disease ‐causing mutations in the promoter and enhancer of the ornithine transcarbamylase gene.
Human mutation. 2018 Apr;39(4):527-36.
Disease ‐causing mutations in the promoter and enhancer of the ornithine transcarbamylase gene.
Human mutation. 2018 Apr;39(4):527-36.
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